Creatinine is a chemical waste molecule which is generated in blood or created by normal breakdown from the muscle metabolism, a molecule of major importance for energy production in muscles. The process of filtration of creatinine done by the kidney’s out of blood and put it in urine to leave from the body. Average 2% of the body’s creatine converted to creatinine every day and transported through the bloodstream to the kidneys.
Normally, the muscle mass in the body is relatively constant, the creatinine level in the blood remains essentially unchanged on daily basis. The kidney’s maintain the blood creatinine in a normal range. Creatinine is chiefly filtered out of the blood by the kidneys, though a small amount is actively secreted by the kidneys into the urine. If the filtering of the kidney is deficient, blood levels then rise. Therefore, creatinine levels in blood and urine used to calculate the creatinine clearance(Cr Cl) which reflects the glomerular filtration rate(GFR), clinically an important aspect to measure the renal function.
However, in cases of severe renal dysfunction, the creatinine clearance rate will be “overestimated” because the active secretion of creatinine will account for a larger fraction of the total creatinine cleared.
A more complete estimation of renal function can be made when interpreting the blood(plasma) concentration of creatinine along with that of urea.
BUN-to-creatinine ratio (the ratio of urea to creatinine) can show other problems besides those intrinsic to the kidney; a urea level raised out of proportion to the creatinine may show a prerenal problem such as volume depletion. Normally, men tend to have higher levels of creatinine because they generally have more skeletal muscle mass than women. It has also been observed that vegetarians to have lower creatinine levels too.
When the kidneys become impaired for any reason, the creatinine level in the blood will rise due to poor clearance by the kidneys,means unable to filter it properly. Abnormally high levels of creatinine thus warn of possible malfunction or failure of the kidneys. It is for this reason that standard blood tests routinely check the amount of creatinine in the blood.
A more precise measure of the kidney function can be estimated by calculating how much creatinine cleared from the body by the kidneys and it is referred to creatinine clearance. Normal levels of creatinine in the blood are about 0.6 to 1.2 milligrams (mg) per deciliter(dl) in adult men and 0.5 to 1.1 milligrams per deciliter in adult women. In the metric system,a milligram is a unit of weight equal to one-thousandth of a gram,and a deciliter is a unit of volume equal to one-tenth of a liter. Whatever the condition that impairs the function of kidneys will probably increase the creatinine level in the blood. It is important to recognize whether the process leading to kidney dysfunction.
The liver is responsible for the urea and passed out-of-body through urine. If kidneys are not able to remove urea from the blood normally, BUN level rises. Heart failure,dehydration,or a diet high in protein can also make BUN level higher. (BUN)test to:see if severe dehydration is present. Kidney disease or blockage of the flow of urine from kidney causes both BUN and creatinine levels to go up. High values BUN can mean kidney injury or disease is present. Kidney damage caused may be because of diabetes or high blood pressure that directly affects. High BUN levels can also be caused by blockage of the urinary tract (by kidney stone or tumor) or low blood flow to the kidneys caused by dehydration or heart failure. A high BUN value is caused by a high-protein diet,or from bleeding in the gastrointestinal digestive tract or respiratory tract. Low values – A low BUN value is caused by a diet very low in protein, malnutrition, or severe liver damage. Drinking excessive amounts of liquid may cause dehydration and cause a low BUN value. A low BUN-to-creatinine ratio may be caused by a diet low in protein. Taking diuretics, which can cause dehydration.
Gastrointestinal bleeds – It is useful for the diagnosis of upper gastrointestinal bleeding in patients who do not present with overt vomiting of blood.
The most common causes of longstanding kidney disease are high blood pressure and diabetes mellitus. Certain drugs can sometimes cause abnormally elevated creatinine levels. Serum creatinine can also transiently rise after ingestion of large amount of dietary meat.
Why Do Kidneys Fail? Most kidney diseases attack neurons,causing them to lose their filtering capacity. Damage to the nephrons may happen quickly,often as result of injury or poisoning. But most kidney diseases destroy neurons slowly and silently. It may take years or even decades for damage to become apparent. The two most common causes of kidney disease are diabetes and high blood pressure.
Signs – Early stages of kidney disease may not feel sick at all, first sign:one may be having feeling of tiredness or itchiness all over the body or frequent headaches. If disease gets worsen, need to urinate more often or less often. May lose your appetite, experience nausea and vomiting. Swelling of hands or feet or may feel numb. May get feeling of drowsiness or having trouble in concentrating, skin may darken and have muscle cramps. Some people may have an incidental finding of severe kidney disease and higher creatinine on routine blood work without having any symptoms at all. In others, depending on the cause of problem, many symptoms may be present including: feeling dehydrated, fatigue, shortness of breath, confusion, or many other nonspecific symptoms.
Urine creatinine (UCr) Creatinine concentration is also checked during standard urine drug tests. High creatinine levels indicate a pure test while low amounts of creatinine in the urine show a manipulated test, either through the addition of water in the sample or by drinking excessive amounts of water.
Acupuncture ‘SuJok’, itself is a powerful medicine, which aids in strengthening the immune system and serves to prevent diseases, control pain and enhance both the ability and quality to act the lives. It has been shown to promote the health and improve the body’s immune function, also helped many people who were not successfully treated through conventional western medicine. Several conditions can be dramatically improved or remedied in full including control of creatinine level or functioning of the kidney’s.
Needless to say, to have positive effective results, one must opt for Acupuncture ‘SuJok’. The beauty of the concept is that each treatment is catered to the needs of an individual patient. SuJok’s energy concept of treatment is on the miniature form of hands and foot of the body. Undoubtedly, one may get positive effective results from the first few sessions. The course of treatment is definitely uneventful.
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