CREATININE


CREATININE  
Creatinine is a chemical waste molecule which is generated in blood  or created by normal breakdown from the muscle metabolism, a molecule of major importance for energy production in muscles. The process of filtration of creatinine  done by the kidney’s out of blood and put it in urine to leave from the body. Average 2% of the body’s creatine converted to creatinine every day and transported through the bloodstream to the kidneys.
Normally, the muscle mass in the body is relatively constant, the creatinine level in the blood remains essentially unchanged on  daily basis. The kidney’s maintain the blood creatinine in a normal range. Creatinine is chiefly filtered out of the blood by the kidneys, though a small amount is actively secreted by the kidneys into the urine. If the filtering of the kidney is deficient, blood levels then rise. Therefore, creatinine levels in blood and urine used to calculate the creatinine clearance(Cr Cl) which reflects the glomerular filtration rate(GFR), clinically an important aspect to measure the renal function.
However, in cases of severe renal dysfunction, the creatinine clearance rate will be “overestimated” because the active secretion of creatinine will account for a larger fraction of the total creatinine cleared.
A more complete estimation of renal function can be made when interpreting the blood(plasma) concentration of creatinine along with that of urea.
BUN-to-creatinine ratio (the ratio of urea to creatinine) can show other problems besides those intrinsic to the kidney; a urea level raised out of proportion to the creatinine may show a prerenal problem such as volume depletion. Normally, men tend to have higher levels of creatinine because they generally have more skeletal muscle mass than women. It has also been observed that vegetarians to have lower creatinine levels too.
When the kidneys become impaired for any reason, the creatinine level in the blood will rise due to poor clearance by the kidneys,means unable to filter it properly. Abnormally high levels of creatinine thus warn of possible malfunction or failure of the kidneys. It is for this reason that standard blood tests routinely check the amount of creatinine in the blood.
A more precise measure of the kidney function can be estimated by calculating how much creatinine cleared from the body by the kidneys and it is referred to creatinine clearance. Normal levels of creatinine in the blood are about 0.6 to 1.2 milligrams (mg) per deciliter(dl) in adult men and 0.5 to 1.1 milligrams per deciliter in adult women. In the metric system,a milligram is a unit of weight equal to one-thousandth of a gram,and a deciliter is a unit of volume equal to one-tenth of a liter. Whatever the condition that impairs the function of kidneys will probably increase the creatinine level in the blood. It is important to recognize whether the process leading to kidney dysfunction.
The liver is responsible for the urea and passed out-of-body through urine. If kidneys are not able to remove urea from the blood normally, BUN level rises. Heart failure,dehydration,or a diet high in protein can also make BUN level higher. (BUN)test  to:see if severe dehydration is present. Kidney disease or blockage of the flow of urine from kidney causes both BUN and creatinine levels to go up. High values BUN can mean kidney injury or disease is present. Kidney damage caused may be because of diabetes or high blood pressure that directly affects. High BUN levels can also be caused by blockage of the urinary tract (by kidney stone or tumor) or low blood flow to the kidneys caused by dehydration or heart failure.  A high BUN value is caused by a high-protein diet,or from bleeding in the gastrointestinal digestive tract or respiratory tract. Low values – A low BUN value is caused by a diet very low in protein, malnutrition, or severe liver damage. Drinking excessive amounts of liquid may cause dehydration and cause a low BUN value. A low BUN-to-creatinine ratio may be caused by a diet low in protein. Taking diuretics, which can cause dehydration.
Gastrointestinal bleeds – It is useful for the diagnosis of upper gastrointestinal bleeding in patients who do not present with overt vomiting of blood.
The most common causes of longstanding kidney disease are high blood pressure and diabetes mellitus. Certain drugs can sometimes cause abnormally elevated creatinine levels. Serum creatinine can also transiently rise after ingestion of large amount of dietary meat.
Why Do Kidneys Fail?  Most kidney diseases attack neurons,causing them to lose their filtering capacity. Damage to the nephrons may happen quickly,often as result of injury or poisoning. But most kidney diseases destroy neurons slowly and silently. It may take years or even decades for damage to become apparent.  The two most common causes of kidney disease are diabetes and high blood pressure.
Signs –  Early stages of kidney disease may not feel sick at all, first sign:one may be having feeling of tiredness or itchiness all over the body or frequent headaches. If disease gets worsen, need to urinate more often or less often. May lose your appetite, experience nausea and vomiting. Swelling of hands or feet or may feel numb. May get feeling of drowsiness or having trouble in concentrating, skin may darken and have muscle cramps. Some people may have an incidental finding of severe kidney disease and higher creatinine on routine blood work without having any symptoms at all. In others, depending on the cause of problem, many symptoms may be present including: feeling dehydrated, fatigue, shortness of breath, confusion, or many other nonspecific symptoms.
 Urine creatinine (UCr) Creatinine concentration is also checked during standard urine drug tests. High creatinine levels indicate a pure test while low amounts of creatinine in the urine show a manipulated test, either through the addition of water in the sample or by drinking excessive amounts of water.
 Acupuncture ‘SuJok’, itself is a powerful medicine, which aids in strengthening the immune system and serves to prevent diseases, control pain and enhance  both the ability and quality to act the lives. It has been shown to promote the health and improve the body’s immune function, also helped many people who were not successfully treated through conventional western medicine.  Several conditions can be dramatically improved or remedied in full including control of creatinine level or functioning of the kidney’s.
 Needless to say, to have positive effective results, one must opt for Acupuncture ‘SuJok’. The beauty of the concept is that each treatment is catered to the needs of an individual patient. SuJok’s energy concept of treatment is on the miniature form of hands and foot of the body. Undoubtedly, one may get positive effective results from the first few sessions. The course of treatment is definitely uneventful.
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URINE Albumin


URINE Albumin 
 Urine with protein or albumin is related to Hypertension or Diabetic.  Kidneys normally prevent large molecules such as albumin from being excreted in the urine, high levels of urinary albumin excretion, called albuminuria, also indicate kidney is some how not functioning properly.  It also reflect dysfunction of endothelial cells throughout the body, which in turn may be a precursor to hypertension or cardiovascular disease.  The urinary albumin : creatinine ratio is a useful measure of renal function used in diabetic renal disease.
 Diabetes is a condition caused by too much glucose(sugar) in the blood.  Normally, the amount of sugar in the blood is controlled by a hormone called insulin, which is produced by the pancreas gland. When food is digested and enters in the bloodstream, insulin moves any glucose out of the blood and into the cells, where it is broken down to produce energy.  However, in those with diabetes, the body is unable to break down the glucose into energy. This is because there is either not enough insulin to move the glucose, or because the insulin that is there, does not work properly.
 The following may also affect the results;  Severe emotional stress.  Strenuous exercise.  Receiving a special dye (contrast media) for a radiology before the urine test. Urine contaminated with vaginal secretions. This test is most often performed when kidney disease is suspected.  
 Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.  This test can help determine if a patient has liver or kidney disease, or if the body is not absorbing enough protein.
 Albumin helps move many small molecules through the blood, including bilirubin, calcium, progesterone, and medications. It plays an important role in keeping the fluid from the blood from leaking out into the tissues.  Because albumin is made by the liver, decreased serum albumin may be a sign of liver disease. It can also result from kidney disease, which allows albumin to escape into the urine. Decreased albumin may also be explained by malnutrition or a low protein diet.
 Blood is made up of two parts: Fluid (plasma or serum) Cells. Plasma contains various substances. Serum is the fluid part that remains after the blood is allowed to clot in a test tube. Specifically, serum is the fluid part of blood after a substance called fibrinogen has been removed.  Cells in the blood include red blood cells, white blood cells, and platelets.   Blood helps move oxygen, nutrients, waste products, and other materials through the body. It helps control body temperature, fluid balance, and  the body’s acid-base balance. 
 Blood clots are the clumps that occur when the blood hardens from a liquid to a solid (coagulates). A blood clot that forms inside a blood vessel or within the heart and remains there is called a thrombus.  A thrombus that travels from the blood vessel or heart to another location in the body is called an embolus. The disorder is called an embolism. For example, an embolus that occurs in the lungs is called a pulmonary embolism.  Sometimes other materials can act like an embolus and block blood flow, including: Air.  Amniotic fluid.  A piece of atherosclerotic plaque.  Fat clumps.  Small pieces of tumor.
 It has been observed with the concept of SuJok Acupuncture it can control in a very effective way irrespective of Diabetes or Hypertension graph. One must opt for the treatment concept through this to have total effectiveness.  The beauty of the acupuncture is that each treatment is catered to the needs of an individual. Acupuncture’s energy concept on palm will be chosen for the overall well being with the objective of increasing circulation of the blood, vital energy and calming the nervous system and removing the toxins, if any.
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